Weight Loss: Your Bodybuilding Guide to Weight Loss Drugs


Weight loss i.e. reducing extra fats or body weight is important for living a healthy and controlled life. The methods used by bodybuilders for achieving their desired weight loss are: dieting, training, steroids and supplements. All these combined with enormous motivation result in an amazingly built body with no excessive fat.

Steroids help bodybuilders to maintain weight loss by repartitioning body fats. Various anabolic androgenic steroids aid in reducing excessive weight and increasing lean body mass. These steroids are also useful in building strong muscles and strengthening the stamina.  

Bodybuilders also control their proteins and carbohydrates intake when they’re on their weight loss cycle.

Training is the most important component of weight loss as it’s great for burning calories. During bodybuilding training, the body is forced to utilize the stored fat which results in a good weight loss.

Weightlifting is also very helpful in this regard and bodybuilders can acquire a maintained and desirable physique by weightlifting 4 to 6 times a week. In addition to it, five to six cardio workouts every week for 30 minutes each can be really beneficial for losing excessive fats.

Cardio workouts include: biking, running and brisk walking etc.

Various supplements also aid in the phase of weight loss. Bodybuilders require supplements in order to meet their high protein needs. Protein powders are found pretty useful in this regard, as they are effective in attaining sufficient protein levels. There are some controversial supplements too which are not recommended to use as their side effects mostly overcome their benefits.


Clenbuterol drug is prescribed to asthma patients as a treatment for the disease. More often, it is used to enhance weight loss or as a performance enhancement drug, mostly utilized by athletes and bodybuilders. This drug is identified as sympathomimetics, which implies that it directly affects the nervous system to execute its performance enhancement function.

Clenbuterol directly affects the beta-2 sympathomimetics receptors along with the beta-1 receptors. These beta-1 receptors directly influence the cardio levels in such a way that it affects the body activity. Clenbuterol performs the same function as performed by epinephrine and generally affects the human body by carrying out the following actions:

⦁    Stimulates the receptors in such a way that it enhances the aerobic activity of the body.

⦁    Quickens the Central Nervous System of the human body.

⦁    Increases the blood flow in the arteries thereby increases the blood pressure

⦁    The transfer of oxygen is also enhanced

⦁    Helps in enhancing the Body Mass Index of the body by efficiently increasing the metabolism rate of the body.

⦁    At the same time it also helps in loosening up of the muscles.

As mentioned above, it increases metabolism rate thereby blood pressure goes high.  This means that the body mass index is increased and at the same time body fats are burned due to increased blood activity.  

The side effects of Clenbuterol includes: hypertension, hypersensitivity, acute myocardial infarction etc. Clenbuterol is banned in many States due to its harmful effects.

Cytomel T3

Cytomel T3 is a synthetic thyroid hormone, That is especially popular among bodybuilders to burn fat.  Cytomel T3 however is not directly produced by the thyroid; in fact it is converted into T4 hormone to carry out its function.

Cytomel T3 is a thyroid agent which directly affects the mitochondria, often referred to as the powerhouses of the cells, to perform its activity enhancement function. It stimulates mitochondria to increase the amount of ATP produced which in turn increases the production of energy in the human body.  This means, respiration activity is increased to produce more heat in the body.

    Following are some of the advantages of the drug:

⦁    Enhances metabolism rate reducing weight effectively

⦁    Helps in breaking down of proteins more efficiently to produce high energy

⦁    Keeps a hormonal balance in the body

⦁    Reduction of Goiter is an apparent affect of this drug

Body builders utilize Cytomel T3 because of its property of eradicating “sticky fats” from the body, thereby helping reduce weight, but not the body mass index, efficiently.

The starting dosage of Cytomel T3 must be low; 25mcgs per day is enough in the start which can gradually be increased as the days pass by.

Over dosage of this prescription is strictly prohibited.  It should not be taken for more than five weeks after which it will start affecting the thyroid gland.

As this is an addictive drug, the dosage must be reduced gradually. Side effects of this Cytomel T3 include: headache, insomnia, diarrhea, sudden weight loss, fever, heat sensitivities and nervousness.  


Xenical is a drug prescribed to obese people which helps them lose all the extra fat from the body.   This weight losing drug is especially prescribed to people having health issues like diabetes, blood pressure or high cholesterol.

Xenical is however most popular amongst the bodybuilders who take this drug as a dietary supplement along with their workout routine.

The main function of this supplement is to absorb the fats and keep away from accumulating inside the body. This drug is basically a gastrointestinal lipase inhibitor which prohibits the fats from settling inside the body, with an absorption rate of thirty percent.

When taken along with hard core exercise and a low fat routine, this prescription is reported to give the best results.

Before using this drug, it is advised to consult a medical practitioner to avoid any kind of complications. However, as a general pattern, it is taken one hour after the consumption of a meal containing fats. Bodybuilders are advised to take it three times a day as their supplement routine.

Following are some of the apparent advantages of using Xenical:

⦁    Reduces weight up to 10% which is the reason why it is one of the most recommended drugs for body builders.

⦁    Helps in lowering blood pressure and the sugar level.

⦁    It is perfectly healthy for the digestive system with no side effects on cardiovascular system

⦁    This drug is non-addictive.

⦁    Tolerability level of this prescription is also high.

Xenical comes with many side effects which include: stomach pain, diarrhea, nausea, rectal pain or sometimes loss of appetite. Other complications include fever, chills or even flu. Teeth problems are also expected along with minor skin rashes. Those who are already on other drugs like insulin or Neprol should also consult with the physician to confirm the compatibility of the medications with this drug. Only those who are above 18 are eligible to take Xenical.


Commonly known as sibutramine, reductil is considered highly effective in treating obesity.  This drug works in two productive ways; first it builds a feeling of fullness so that the patient feels satisfied in a flash even after an intake of little portions of meal and it also reduces the frequency of cravings for unhealthy food. Secondly, it aids in restraining the metabolism of the body from slowing down.

The most active ingredient found in reductil is sibutramine hydrochloride monohydrate which is considered efficacious for reducing weight.  The working of reductil is different from traditional weight loss pills as it operates by obstructing the re-uptake of a neurotransmitter known as serotonin.  It results in the presence of a greater quantity of serotonin in the brain that is linked with smaller appetite.

Reductil is found in five, ten and fifteen milligrams doses and is only taken orally. It is mostly recommended to people who have tried different weight loss methods but nothing worked and having body mass index BMI of over 30 kg/m2. Not every person using reductil reports side effects but some of its common side effects are: nausea, hot flushes, headache, insomnia, constipation, sweaty hands and dry mouth etc. This drug is not considered an addictive medicine as it is licensed to use for long durations for treating obesity.


Sibutramine, a medicine which has been withdrawn from the U.S and other regions market from October 2010, was primarily used to assist overweight people in losing weight by adjusting neurotransmitters inside the brain.

Neurotransmitters are defined as chemicals generated and released through nerves for communicating with other nerves. The neurotransmitters released may stick to other nerves or may be absorbed again by those nerves that usually release them. This processed is called reuptake. Thus, sibutramine used to obstruct reuptake of serotonin, norepinephrine and neurotransmitters dopamine. This obstruction of the reuptake of neurotransmitters alters neurotransmitters balance inside the nerve cells which affects the interaction and function of the nerve.

Sibutramine belongs to the “appetite suppressants” class of medications that help in reducing the cravings and hunger through alteration in the appetite control centers present in the brain.

Sibutramine was considered an effective drug for weight loss when taken with a healthy low calorie diet and exercise. It was also recommended for treating obesity related to high cholesterol, diabetes and high blood pressure.

This medicine was not commonly prescribed and people suffering from anorexia nervosa were not allowed to take it. Bodybuilders who used to take sibutramine were likely to achieve a reduction of 5 to 10% from their weight.

The reason for its withdrawal was some of its side effects that were found potentially hazardous and life threatening.


Diuretics, also called water pills, are medications that expel fluids from the body by increasing urination. Bodybuilders who need to cut down more weight in a short span of time turn to diuretics as the less fluid they have in their body, the less they will weigh, and also more muscle definition.  

There are several categories of diuretics but all of them work more or less differently.  Major over the counter diuretics work on the kidneys for expelling salts and water.  Other water pills increase blood supply to the kidneys and some drugs increase the filtration rate of the kidneys.

Diuretics is also used for treating conditions such as high blood pressure, kidney diseases, heart failure and liver cirrhosis, but it is being advertised more as a weight reducing drug to normal users.

Diuretics is not considered a healthy way to reduce weight, as it is not proven to help in the fat reduction. This drug only aids in reducing the amount of liquid retained in the body. This weight loss is temporary and as soon as a user eats or drinks something, his body starts replacing the lost liquids, which results in a regain in his weight.

Other than that abusing diuretics may result into life threatening conditions like dehydration and critical potassium deficiencies. Moreover, some users also experience cramping or weakness of muscles, irregular heartbeat, fatigue and nausea.